Sublingual Tablet MTX-101

About a new medication in development for the treatment of migraine

MTX-101 is designed to work differently than the current migraine drugs, Nurtec and Qulipta. It targets a different receptor which modulates the effects of both CGRP and PACAP, which are thought to cause migraine. Nurtec and Qulipta only target the CGRP receptor.

As MTX-101 activates a different receptor, it is highly likely that it will prove effective in those patients who have not responded to Nurtec or Qulipta.

MTX-101 has proven safe with few side effects in long-term usage.

MTX-101 is currently being tested in Phase II clinical studies.

About Manistee Therapeutics Migraine

MANISTEE THERAPEUTICS

MIGRAINE TREATMENT

Innovative new study on pain relief

Migraine is a global problem affecting greater than 10% of the population

(859 million globally)

More than 44 million individuals are affected in the USA.